During the recent COVID-19 surge driven by SARS-CoV-2 Omicron variant, people receiving a booster dose were 21 times less likely to die from COVID-19, compared with patients who were unvaccinated. They were seven times less likely to be hospitalized, according to the CDC. The updated recommendations acknowledge the increased risk of severe disease in certain populations including seniors and those 50 or older with multiple underlying conditions, the CDC added.
The FDA noted that it was basing its action on safety and immune response information reported to the agency, information on effectiveness reported by vaccine manufacturers, and a summary of safety data provided by the Israeli health ministry on the administration of a fourth dose to 700,000 people—the vast majority of whom were between 60 and 100 years old.
Author: American Medical Association